Previous studies have found that smoking cigarettes can accelerate the start of menopause with its well known hot flashes. It also contributes to an increased risk of postmenopausal osteoporosis. In addition to that…
The current study tried to explain why some women who smoke are even more prone o hot flashes than others, and found that specific genes are involved…
Firstly, these (variant) genes are involved in the metabolism of hormones, BUT…
Secondly, these genes also activate some toxins contained in the tobacco smoke, aggravating their effect on the body.
While women who smoke during menopause are at higher risk of hot flashes anyway, those who carry the specific gene variants are even more susceptible to it compared to those smokers who do not carry these genes. This finding was accepted and published by The Endocrine Society’s Journal of Clinical Endocrinology and Metabolism (JCEM).
These findings were observed during a study that started eleven years ago – originally intended as a study of reproductive aging. The study group involved almost 300 women in their “later reproductive years”, with the intent of studying their physiological changes as they progress through menopause and beyond. The group included women who smoked and use alcohol, so as to obtain information on behavioural and lifestyle influences as well.
Any woman who smokes is likely to trigger the onset of menopause sooner, and is she happens to be carrying a set of (specific) variant genes, the effects are likely to be even worse, including the hot flashes, and the greater risk of developing postmenopausal osteoporosis.
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Author: Karien Venter